Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 393
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 393
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 394
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 394
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 395
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 395
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Summary: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. [provided by RefSeq, Nov 2020] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_0049 | 2021.04 | 10X Genomics | Lung | Normal | 1702 | Link |
Vthunter_110082 | 2018.05 | Drop-seq | Pallium | Normal | 4187 | Link |
Featureplot of receptors
Expression: Biased expression in small intestine (RPKM 93.7), duodenum (RPKM 69.0) and 5 other tissues